

| 货号 | MY195014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse CD45/PTPRC Polyclonal Antibody (MY195014) is a rabbit polyclonal antibody detecting Ptprc in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD45/PTPRC (Thr202-Phe563). | ||||||||
| 经测试应用 | WB | ||||||||
| 靶标 | Receptor-type tyrosine-protein phosphatase C, 3.1.3.48, Leukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P06800 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Receptor-type tyrosine-protein phosphatase C (CD45/PTPRC) is a ~144 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PTPRC polyclonal antibody at 1ug/mL on various samples.
Lane 1: RAW264.7 cell lysate
Lane 2: Mouse spleen lysate
Lane 3: Mouse thymus lysate



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