Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody (MW601014)

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概述
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参考文献
产品说明书

概述

货号

MW601014

品牌

abinScience

描述

Anti-Mouse CD110/MPL Polyclonal Antibody (MW601014) is a rabbit polyclonal antibody detecting CD110 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Mouse CD110/MPL (Ser394-Ile483).

靶标

Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, Mpl, Tpor

纯化方式

Purified by antigen affinity column.

Accession号

Q08351

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Thrombopoietin receptor (CD110/MPL) is a ~69 kDa protein. Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Upon activation by THPO, induces rapid tyrosine phosphorylation and activation of JAK2, providing docking sites for many signaling proteins such as STAT5, SHIP/INPP5D, GRB2, SOS1 and PI3K. In turn, These signaling cascades lead to the proliferation, survival, and differentiation of megakaryocytes, ultimately leading to increased platelet production.

1. Alexander, WS. et al. (1996) Blood 87, 2162-70. PMID: 8630375

2. Drachman, JG. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 2350-5. PMID: 9122198

3. Solar, GP. et al. (1998) Blood 92, 4-10. PMID: 9639492

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody (MW601014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody (MW601014)

概述

图片

参考文献

产品说明书

相关产品推荐

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