

| 货号 | MW431014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse CD79β/CD79B Polyclonal Antibody (MW431014) is a rabbit polyclonal antibody detecting CD79b in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD79β/CD79B (Val26-Ser145). | ||||||||
| 经测试应用 | WB | ||||||||
| 靶标 | B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Cd79b, Igb | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P15530 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~25 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy). | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-CD79B polyclonal antibody at CD79B on various samples.
Lane 1: Daudi cell lysate
Lane 2: HL-60 cell lysate



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