

| 货号 | MB904014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse ITGB8 Polyclonal Antibody (MB904014) is a rabbit polyclonal antibody detecting Itgb8 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse ITGB8 (Val106-Ser466). | ||||||||
| 靶标 | Integrin beta-8, Itgb8 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q0VBD0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Integrin beta-8 (ITGB8) is a ~84 kDa protein. Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis. 1. Edwards, JP. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2843-9. PMID: 25127859 2. Zhu, J. et al. (2002) Development (Cambridge, England) 129, 2891-903. PMID: 12050137 3. Proctor, JM. et al. (2005) The Journal of neuroscience : the official journal of the Society for Neuroscience 25, 9940-8. PMID: 16251442 | ||||||||
| Note | For research use only. |

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