Anti-Mouse GGT5 Polyclonal Antibody (MW691014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

MW691014

品牌

abinScience

描述

Anti-Mouse GGT5 Polyclonal Antibody (MW691014) is a rabbit polyclonal antibody detecting Ggt5 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse GGT5 (Ser30-Tyr573).

靶标

Glutathione hydrolase 5 proenzyme, 3.4.19.13, Gamma-glutamyl leukotrienase, GGL, Gamma-glutamyltransferase 5, GGT 5, 2.3.2.2, Gamma-glutamyltransferase-like activity 1, Gamma-glutamyltranspeptidase 5, Leukotriene-C4 hydrolase, 3.4.19.14, Glutathione hydrolase 5 heavy chain, Glutathione hydrolase 5 light chain, Ggt5, Ggtla1

纯化方式

Purified by antigen affinity column.

Accession号

Q9Z2A9

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Glutathione hydrolase 5 proenzyme (GGT5) is a ~61 kDa protein. Cleaves the gamma-glutamyl bond of extracellular glutathione tripeptide (gamma-Glu-Cys-Gly) and certain glutathione conjugates. Hydrolyzes glutathione releasing L-Glu and Cys-Gly dipeptide which is further metabolized to maintain extracellular cysteine levels but also to provide cysteine necessary for intracellular glutathione synthesis. Among glutathione-S-conjugates metabolizes leukotriene C4 (LTC4) and S-geranylgeranyl-glutathione (GGG), but is inactive toward gamma-glutamyl leucine. Converts extracellular LTC4 to LTD4 during acute inflammatory response. Acts as a negative regulator of GGG bioactivity.

1. Shi, ZZ. et al. (2001) Molecular and cellular biology 21, 5389-95. PMID: 11463821

2. Han, B. et al. (2002) The American journal of pathology 161, 481-90. PMID: 12163373

3. Lu, E. et al. (2019) Nature 567, 244-248. PMID: 30842656

4. Carter, BZ. et al. (1998) The Journal of biological chemistry 273, 28277-85. PMID: 9774450

5. Gallman, AE. et al. (2021) Science immunology 6. PMID: 34088745

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse GGT5 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse GGT5 Polyclonal Antibody (MW691014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse GGT5 Polyclonal Antibody (MW691014)

概述

图片

参考文献

产品说明书

相关产品推荐

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