Anti-Mouse SLC16A1/MCT1 Polyclonal Antibody (MX905014)

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概述
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参考文献
产品说明书

概述

货号

MX905014

品牌

abinScience

描述

Anti-Mouse SLC16A1/MCT1 Polyclonal Antibody (MX905014) is a rabbit polyclonal antibody detecting Slc16a1 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Mouse SLC16A1/MCT1 (Met195-Arg254).

靶标

Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1, Slc16a1, Mct1

纯化方式

Purified by antigen affinity column.

Accession号

P53986

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Monocarboxylate transporter 1 (SLC16A1/MCT1) is a ~53 kDa protein. Bidirectional proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH. The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major lactate exporter. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

1. Pullen, TJ. et al. (2012) Diabetes 61, 1719-25. PMID: 22522610

2. Lengacher, S. et al. (2013) PloS one 8, e82505. PMID: 24367518

3. Reddy, A. et al. (2020) Cell 183, 62-75.e17. PMID: 32946811

Note

For research use only.

图片

参考文献

产品说明书

Anti-Mouse SLC16A1/MCT1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse SLC16A1/MCT1 Polyclonal Antibody (MX905014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse SLC16A1/MCT1 Polyclonal Antibody (MX905014)

概述

图片

参考文献

产品说明书

相关产品推荐

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