

| 货号 | MV286014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse RNLS/Renalase Polyclonal Antibody (MV286014) is a rabbit polyclonal antibody detecting Renalase in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse RNLS/Renalase (Ala18-Ile342). | ||||||||
| 靶标 | Renalase, 1.6.3.5, Monoamine oxidase-C, MAO-C, mMAO-C, Rnls | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | A7RDN6 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Renalase (RNLS) is a ~37 kDa protein. Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. | ||||||||
| Note | For research use only. |

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