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Anti-Mouse TRPV1 Polyclonal Antibody (MV711014)

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概述
货号MV711014
品牌abinScience
描述
Anti-Mouse TRPV1 Polyclonal Antibody (MV711014) is a rabbit polyclonal antibody detecting TrpV1 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse TRPV1 (Arg115-Arg433).
靶标Transient receptor potential cation channel subfamily V member 1, TrpV1, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1, Trpv1
纯化方式Purified by antigen affinity column.
Accession号Q704Y3
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Transient receptor potential cation channel subfamily V member 1 (TRPV1) is a ~94 kDa protein. Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius.

1. Hu, HZ. et al. (2004) The Journal of biological chemistry 279, 35741-8. PMID: 15194687
2. Correll, CC. et al. (2004) Neuroscience letters 370, 55-60. PMID: 15489017
3. Caterina, MJ. et al. (2000) Science (New York, N.Y.) 288, 306-13. PMID: 10764638
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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