

| 货号 | MV727014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Mouse CIDEC Polyclonal Antibody (MV727014) is a rabbit polyclonal antibody detecting Cidec in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 种属反应性 | Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CIDEC (Arg41-Cys178). | ||||||||
| 靶标 | Lipid transferase CIDEC, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27, Cidec, Fsp27 | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P56198 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lipid transferase CIDEC is a ~27 kDa protein. Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. 1. Keller, P. et al. (2008) The Journal of biological chemistry 283, 14355-65. PMID: 18334488 2. Gong, J. et al. (2011) The Journal of cell biology 195, 953-63. PMID: 22144693 3. Xu, W. et al. (2016) The Journal of biological chemistry 291, 4282-93. PMID: 26733203 4. Wang, J. et al. (2018) The Journal of biological chemistry 293, 19330-19343. PMID: 30361435 5. Qian, K. et al. (2023) Nature 613, 160-168. PMID: 36477540 6. Toh, SY. et al. (2008) PloS one 3, e2890. PMID: 18682832 | ||||||||
| Note | For research use only. |

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