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Anti-Mouse CIDEC Polyclonal Antibody (MV727014)

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概述
货号MV727014
品牌abinScience
描述
Anti-Mouse CIDEC Polyclonal Antibody (MV727014) is a rabbit polyclonal antibody detecting Cidec in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Mouse CIDEC (Arg41-Cys178).
靶标Lipid transferase CIDEC, Cell death-inducing DFFA-like effector protein C, Fat-specific protein FSP27, Cidec, Fsp27
纯化方式Purified by antigen affinity column.
Accession号P56198
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Lipid transferase CIDEC is a ~27 kDa protein. Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1.

1. Keller, P. et al. (2008) The Journal of biological chemistry 283, 14355-65. PMID: 18334488
2. Gong, J. et al. (2011) The Journal of cell biology 195, 953-63. PMID: 22144693
3. Xu, W. et al. (2016) The Journal of biological chemistry 291, 4282-93. PMID: 26733203
4. Wang, J. et al. (2018) The Journal of biological chemistry 293, 19330-19343. PMID: 30361435
5. Qian, K. et al. (2023) Nature 613, 160-168. PMID: 36477540
6. Toh, SY. et al. (2008) PloS one 3, e2890. PMID: 18682832
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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