

| 货号 | HY385014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human RARB Polyclonal Antibody (HY385014) is a rabbit polyclonal antibody detecting RARB in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RARB (Leu205-Ser451). | ||||||||
| 靶标 | Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B member 2, RARB, HBV-activated protein, RAR-beta, RAR-epsilon, NR1B2, HAP | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P10826 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Retinoic acid receptor beta (RARB) is a ~50 kDa protein. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. 1. Hauksdottir, H. et al. (2003) Molecular endocrinology (Baltimore, Md.) 17, 373-85. PMID: 12554770 2. Chandra, V. et al. (2017) Nature communications 8, 868. PMID: 29021580 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-RARB polyclonal antibody at 1ug/mL on various samples.
Lane 1: HUVEC cell lysate
Lane 2: A431 cell lysate
Lane 3: A549 cell lysate



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