Anti-Human CDC5L Polyclonal Antibody (HA841014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HA841014

品牌

abinScience

描述

Anti-Human CDC5L Polyclonal Antibody (HA841014) is a rabbit polyclonal antibody detecting CDC5L in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human CDC5L (Ser591-Glu851).

靶标

CDC5L, PCDC5RP, KIAA0432, Cdc5-like protein, Cell division cycle 5-like protein, Pombe cdc5-related protein

纯化方式

Purified by antigen affinity column.

Accession号

Q99459

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Cell division cycle 5-like protein (CDC5L) is a ~92 kDa protein. DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638

2. Grote, M. et al. (2010) Molecular and cellular biology 30, 2105-19. PMID: 20176811

3. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

4. Zhang, X. et al. (2017) Cell 169, 918-929.e14. PMID: 28502770

5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 29301961

6. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106

7. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316

8. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 30705154

9. Zhang, X. et al. (2019) Cell research 29, 274-285. PMID: 30728453

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-KANK2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse lung lysate

参考文献

产品说明书

Anti-Human CDC5L Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CDC5L Polyclonal Antibody (HA841014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CDC5L Polyclonal Antibody (HA841014)

概述

图片

参考文献

产品说明书

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