

| 货号 | VK746014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-HSV-1/HHV-1 gE Polyclonal Antibody (VK746014) is a rabbit polyclonal antibody detecting HSV-1/HHV-1 gE in ELISA, IHC, WB.
Highlights
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| 种属反应性 | Human herpesvirus 1 (HHV-1) (Human herpes simplex virus 1) (HSV-1) | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant HSV-1/HHV-1 gE (Lys24-Arg419). | ||||||||
| 靶标 | gE, Envelope glycoprotein E | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P04488 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Envelope glycoprotein E (gE) is a ~59 kDa protein. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips. | ||||||||
| Note | For research use only. |

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