Anti-PDCD6IP Polyclonal Antibody (HV421014)

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100ug

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概述
图片
参考文献
产品说明书

概述

货号

HV421014

品牌

abinScience

描述

Anti-PDCD6IP Polyclonal Antibody (HV421014) is a rabbit polyclonal antibody detecting PDCD6IP in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PDCD6IP (Glu174-Ala383).

靶标

ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, AIP1, ALIX, KIAA1375, PDCD6IP, Programmed cell death 6-interacting protein, PDCD6-interacting protein

纯化方式

Purified by antigen affinity column.

Accession号

Q8WUM4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Programmed cell death 6-interacting protein (PDCD6IP) is a ~96 kDa protein. Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.

1. Matsuo, H. et al. (2004) Science (New York, N.Y.) 303, 531-4. PMID: 14739459

2. Carlton, JG. et al. (2007) Science (New York, N.Y.) 316, 1908-12. PMID: 17556548

3. Morita, E. et al. (2007) The EMBO journal 26, 4215-27. PMID: 17853893

4. Carlton, JG. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 10541-6. PMID: 18641129

5. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-PDCD6IP polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: K562 cell lysate
Lane 4: PC-12 cell lysate
Lane 5: Mouse liver lysate
Lane 6: Rat liver lysate

参考文献

产品说明书

Anti-PDCD6IP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PDCD6IP Polyclonal Antibody (HV421014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-PDCD6IP Polyclonal Antibody (HV421014)

概述

图片

参考文献

产品说明书

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