Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143)

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货号	HP849143
品牌	abinScience
种属反应性	Human
应用	FCM
宿主	Mouse
同种型	IgG1
克隆号	21F12
偶联物	PerCP
克隆类型	Monoclonal
靶标	Abeta42, Beta-APP42, Amyloid-beta protein 42, amyloid beta A4 precursor protein, Amyloid-beta A4 protein, Abeta 1-42
内毒素水平	Please contact with the lab for this information.
纯度	>95% as determined by SDS-PAGE.
相关产品	Mouse IgG1 Recombinant Isotype Control Antibody (HyHEL-10), PerCP
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P05067
RRID	Anti-Human Abeta42/Beta-APP42 Antibody (21F12), PerCP (abinScience Cat# HP849143, RRID:AB_3725381)
状态	Liquid
保存溶液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
稳定性和存储	The antibody solution should be stored between 2 to 8°C in dark. DO NOT FREEZE!
背景	Amyloid-beta precursor protein (Abeta 42/Beta-APP 42) is a ~86 kDa protein. Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP. 1. Baumkötter, F. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 11159-72. PMID: 25122912 2. Satpute-Krishnan, P. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 16532-7. PMID: 17062754 3. Seamster, PE. et al. (2012) Physical biology 9, 055005. PMID: 23011729
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

产品说明书

Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP.pdf

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Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143)

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参考文献

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Anti-Human Abeta42/Beta-APP42 Recombinant Antibody (21F12), PerCP (HP849143)

概述

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参考文献

产品说明书

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