Anti-Mouse MMP3 Recombinant Antibody (CH01) (MY526013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

MY526013

abinScience

种属反应性

Human, Mouse, Rat

ELISA, IF

IgG1, kappa

SL-1, Transin-1, MMP-3, MMP3, Matrix metalloproteinase-3, Stromelysin-1, STMY1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P28862

Anti-Mouse MMP3 Antibody (CH01) (abinScience Cat# MY526013, RRID:AB_3725632)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Stromelysin-1 (MMP3) is a ~53 kDa protein. Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Also acts intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage.

1. Kim, YS. et al. (2007) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 179-87. PMID: 17116747

2. Feng, T. et al. (2022) Antiviral research 206, 105388. PMID: 35940311

For research use only.

Isotype Control

Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407)

SDS-PAGE

SDS-PAGE for Anti-Mouse MMP3 Antibody (CH01)
Bioactivity

Detects recombinant human MMP3 (Catalog No: HY526012) in indirect ELISA
Flow cytometry

Flow-cytometry using anti-human MMP3 antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human MMP3 monoclonal antibody (Catalog MY526013, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Rat IgG H&L Polyclonal Antibody, FITC (abinScience: RF690334) and cells analysed on a NovoCyte Flow Cytometer.

产品说明书

Anti-Mouse MMP3 Recombinant Antibody (CH01).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

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Anti-Mouse MMP3 Recombinant Antibody (CH01) (MY526013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse MMP3 Recombinant Antibody (CH01) (MY526013)

概述

图片

参考文献

产品说明书

相关产品推荐

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