Anti-Mouse p53 Recombinant Antibody (PAb242) (MY039013)

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规格：

50ug
100ug
1mg

数量：

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概述
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参考文献
产品说明书

MY039013

abinScience

种属反应性

Mouse

ELISA, IF, IHC, IP, RIA, WB

Monoclonal

IgG2a, kappa

PAb242

Antigen NY-CO-13, Cellular tumor antigen p53, P53, Tumor suppressor p53, TP53, Phosphoprotein p53

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P02340

Anti-Mouse TP53/p53 Antibody (PAb242) (abinScience Cat# MY039013, RRID:AB_3725644)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Cellular tumor antigen p53 (TP53) is a ~43 kDa protein. Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.

1. Allton, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 11612-6. PMID: 19556538

2. Huarte, M. et al. (2010) Cell 142, 409-19. PMID: 20673990

3. Vaseva, AV. et al. (2012) Cell 149, 1536-48. PMID: 22726440

4. Miki, T. et al. (2013) Nature communications 4, 2444. PMID: 24051492

For research use only.

Bioactivity

Detects Recombinant Mouse TP53/p53 Protein, N-His (Cat No.: MY039012) in indirect ELISA.

产品说明书

Anti-Mouse p53 Recombinant Antibody (PAb242).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse p53 Recombinant Antibody (PAb242) (MY039013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse p53 Recombinant Antibody (PAb242) (MY039013)

概述

图片

参考文献

产品说明书

相关产品推荐

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