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Anti-Mouse STAT3 Recombinant Antibody (SAA0274) (MW708013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号MW708013
品牌abinScience
种属反应性Human, Mouse
应用ELISA, IP, WB
同种型IgG1, kappa
克隆号SAA0274
靶标Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P42227
RRIDAnti-Mouse STAT3 Antibody (SAA0274) (abinScience Cat# MW708013, RRID:AB_3725645)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Signal transducer and activator of transcription 3 (STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

1. Ren, F. et al. (2013) Cellular signalling 25, 2272-80. PMID: 23917203
2. Ren, F. et al. (2015) FEBS letters 589, 1890-6. PMID: 26026268
3. Bates, SH. et al. (2003) Nature 421, 856-9. PMID: 12594516
4. Gonzalez, RR. et al. (2006) The Journal of biological chemistry 281, 26320-8. PMID: 16825198
5. Kostromina, E. et al. (2010) Endocrinology 151, 2050-9. PMID: 20215569
6. Manukyan, I. et al. (2010) Journal of cellular and molecular medicine 14, 1707-16. PMID: 19538478
7. Choi, SM. et al. (2013) The Journal of experimental medicine 210, 551-61. PMID: 23401489
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Mouse STAT3 Antibody (SAA0274)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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