Anti-Phospho-HTRA2 (pS212) Recombinant Antibody (P6.C12) (HT447013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT447013

abinScience

种属反应性

Human

IHC, IP, WB

Mouse

Monoclonal

IgG2a, kappa

P6.C12

High temperature requirement protein A2, OMI, HtrA2, PRSS25, Serine protease 25, Serine proteinase OMI, Serine protease HTRA2, mitochondrial, HTRA2, Omi stress-regulated endoprotease

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O43464

Anti-Phospho-HTRA2 (pS212) Antibody (P6.C12) (abinScience Cat# HT447013, RRID:AB_3725755)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Serine protease HTRA2, mitochondrial (pHTRA2) is a ~48 kDa protein. Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes apoptosis by either relieving the inhibition of BIRC proteins on caspases, leading to an increase in caspase activity; or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves BIRC6 and relieves its inhibition on CASP3, CASP7 and CASP9, but it is also prone to inhibition by BIRC6. Cleaves THAP5 and promotes its degradation during apoptosis.

1. Savopoulos, JW. et al. (2000) Protein expression and purification 19, 227-34. PMID: 10873535

2. Bartke, T. et al. (2004) Molecular cell 14, 801-11. PMID: 15200957

3. Hunkeler, M. et al. (2023) Science (New York, N.Y.) 379, 1105-1111. PMID: 36758104

4. Ehrmann, JF. et al. (2023) Science (New York, N.Y.) 379, 1117-1123. PMID: 36758105

5. Balakrishnan, MP. et al. (2009) American journal of physiology. Heart and circulatory physiology 297, H643-53. PMID: 19502560

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Phospho-HTRA2 (pS212) Antibody (P6.C12)

产品说明书

Anti-Phospho-HTRA2 (pS212) Recombinant Antibody (P6.C12).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Phospho-HTRA2 (pS212) Recombinant Antibody (P6.C12) (HT447013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Phospho-HTRA2 (pS212) Recombinant Antibody (P6.C12) (HT447013)

概述

图片

参考文献

产品说明书

相关产品推荐

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