

| 货号 | HB851013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | IHC, IP, WB | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA0304 | ||||
| 靶标 | cAMP-responsive element-binding protein 1, CREB-1, CREB1, Cyclic AMP-responsive element-binding protein 1 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P16220 | ||||
| RRID | Anti-Phospho-CREB1 (pS133) Antibody (SAA0304) (abinScience Cat# HB851013, RRID:AB_3725765) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Cyclic AMP-responsive element-binding protein 1 (p-CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling. 1. Conkright, MD. et al. (2003) Molecular cell 12, 413-23. PMID: 14536081 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Phospho-CREB1 (pS133) Antibody (SAA0304)



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