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Anti-Phospho-CREB1 (pS133) Recombinant Antibody (SAA0304) (HB851013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HB851013
品牌abinScience
种属反应性Human
应用IHC, IP, WB
同种型IgG2a, kappa
克隆号SAA0304
靶标cAMP-responsive element-binding protein 1, CREB-1, CREB1, Cyclic AMP-responsive element-binding protein 1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P16220
RRIDAnti-Phospho-CREB1 (pS133) Antibody (SAA0304) (abinScience Cat# HB851013, RRID:AB_3725765)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Cyclic AMP-responsive element-binding protein 1 (p-CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling.

1. Conkright, MD. et al. (2003) Molecular cell 12, 413-23. PMID: 14536081
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Phospho-CREB1 (pS133) Antibody (SAA0304)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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