

| 货号 | HF743033 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-Human TG/Thyroglobulin Nanobody (SAA1339) [SAA1339] (HF743033) is a alpaca monoclonal antibody detecting Thyroglobulin in ELISA, IF, IHC, RIA, SPR. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||
| 应用 | ELISA, IF, IHC, RIA, SPR | ||||
| 宿主 | Alpaca | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | VHH-8His-Cys-tag | ||||
| 克隆号 | SAA1339 | ||||
| 靶标 | Thyroglobulin, Tg, TG | ||||
| 内毒素水平 | < 10 EU/mg as determined by LAL method. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Purified by Nickel column. | ||||
| Accession号 | P01266 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. 1. Caputo, M. et al. (2007) Clinical endocrinology 67, 351-7. PMID: 17532758 2. Coscia, F. et al. (2020) Nature 578, 627-630. PMID: 32025030 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TG/Thyroglobulin Nanobody (SAA1339)



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