Anti-Human beta-2 Adrenergic R/ADRB2 Recombinant Nanobody (SAA1015) (HY357023)

价格: --

规格：

50ug
100ug
1mg

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

HY357023

品牌

abinScience

描述

Anti-Human ADRB2 Nanobody (SAA1015) [SAA1015] (HY357023) is a alpaca monoclonal antibody detecting ADRB2 in ELISA. Suitable for Human.

种属反应性

Human

应用

ELISA

宿主

Alpaca

克隆类型

Monoclonal

同种型

VHH-8His-Cys-tag

克隆号

SAA1015

靶标

Beta-2 adrenergic receptor, ADRB2R, Beta-2 adrenoreceptor, ADRB2, B2AR, Beta-2 adrenoceptor

内毒素水平

< 10 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

P07550

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Beta-2 adrenergic receptor is a ~46 kDa protein. G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, activating bifurcated signaling pathways. ADRB2 binds epinephrine (Epi) with an approximately 30-fold greater affinity than norepinephrine (NE). In the heart, Epi- and NE-activated ADRB2 induces rapid and slow cardiomyocyte contraction rate, respectively. Both NE and Epi promote coupling to G(s)/PKA pathway to regulate myocyte contraction rate. Epi also promotes ADRB2 coupling to G(i) proteins to exert cardioprotective effects especially in the conditions of hypoxia and oxidative stress through the G(i)/PI3K/Akt signaling pathway.

1. Zhu, WZ. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 1607-12. PMID: 11171998

2. Wang, Y. et al. (2008) The Journal of biological chemistry 283, 1799-807. PMID: 18056263

3. Allen, JM. et al. (1988) The EMBO journal 7, 133-8. PMID: 2834198

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Human ADRB2 Nanobody (SAA1015)

参考文献

产品说明书

Anti-Human beta-2 Adrenergic R/ADRB2 Recombinant Nanobody (SAA1015).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human beta-2 Adrenergic R/ADRB2 Recombinant Nanobody (SAA1015) (HY357023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human beta-2 Adrenergic R/ADRB2 Recombinant Nanobody (SAA1015) (HY357023)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价