



| 货号 | HY105013 | ||||||
|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||
| 描述 |
Anti-Human CD331/FGFR1 Nanobody (SAA1366) [SAA1366] (HY105013) is a alpaca monoclonal antibody detecting FGFR1 in ELISA, IF, SPR, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||
| 应用 | ELISA, IF, SPR, WB | ||||||
| 宿主 | Alpaca | ||||||
| 克隆类型 | Monoclonal | ||||||
| 同种型 | VHH-8His-Cys-tag | ||||||
| 克隆号 | SAA1366 | ||||||
| 靶标 | FLT2, HBGFR, BFGFR, FGFR-1, CEK, Fibroblast growth factor receptor 1, FGFR1, bFGF-R-1, Fms-like tyrosine kinase 2, FGFBR, FLT-2, CD331, Basic fibroblast growth factor receptor 1, FLG, Proto-oncogene c-Fgr, N-sam | ||||||
| 内毒素水平 | < 10 EU/mg as determined by LAL method. | ||||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||||
| 纯化方式 | Purified by Nickel column. | ||||||
| Accession号 | P11362 | ||||||
| 状态 | Liquid | ||||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 背景 | Fibroblast growth factor receptor 1 (CD331/FGFR1) is a ~91 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD331/FGFR1 Nanobody (SAA1366)

Detects recombinant CD331 (Catalog No: HY105011) in indirect ELISA.





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