

| 货号 | HX193023 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-Human BACE1 Nanobody (SAA1336) [SAA1336] (HX193023) is a alpaca monoclonal antibody detecting BACE1 in ELISA. Suitable for Human.
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| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 宿主 | Alpaca | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | VHH-8His-Cys-tag | ||||
| 克隆号 | SAA1336 | ||||
| 靶标 | BACE1, Memapsin-2, KIAA1149, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, BACE, Beta-site APP cleaving enzyme 1, Beta-secretase 1, Aspartyl protease 2, ASP2, Membrane-associated aspartic protease 2, BACE1 | ||||
| 内毒素水平 | < 10 EU/mg as determined by LAL method. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Purified by Nickel column. | ||||
| Accession号 | P56817 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Beta-secretase 1 (BACE1) is a ~55 kDa protein. Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves CHL1. 1. Hussain, I. et al. (1999) Molecular and cellular neurosciences 14, 419-27. PMID: 10656250 2. Lin, X. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 1456-60. PMID: 10677483 3. Okada, H. et al. (2010) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 24, 2783-94. PMID: 20354142 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human BACE1 Nanobody (SAA1336)



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