

| 货号 | HP529013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1381 | ||||
| 靶标 | Abeta40, Beta-APP40, Amyloid-beta protein 40, amyloid beta A4 precursor protein, Amyloid-beta A4 protein | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P05067 | ||||
| RRID | Anti-Human Abeta40/Beta-APP40 Antibody (SAA1381) (abinScience Cat# HP529013, RRID:AB_3726900) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Amyloid-beta precursor protein (Abeta 40/Beta-APP 40) is a ~86 kDa protein. Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(o) and JIP. _x005F_x000D_ _x005F_x000D_1. Baumkötter, F. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 11159-72. PMID: 25122912 _x005F_x000D_
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2. Satpute-Krishnan, P. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 16532-7. PMID: 17062754 _x005F_x000D_
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3. Seamster, PE. et al. (2012) Physical biology 9, 055005. PMID: 23011729 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human Abeta40/Beta-APP40 Antibody (SAA1381).



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