| 靶标 | Gag-Pol polyprotein, Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide 1, SP1, p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, 3.4.23.16, PR, Retropepsin, Reverse transcriptase/ribonuclease H, 2.7.7.49, 2.7.7.7, 3.1.26.13, Exoribonuclease H, 3.1.13.2, p66 RT, p51 RT, p15, Integrase, IN, 2.7.7.-, 3.1.-.-, gag-pol |
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| 背景 | Gag-Pol polyprotein (Matrix proteinp17/MA) is a ~163 kDa protein. Gag-Pol polyprotein and Gag polyprotein may regulate their own translation, by the binding genomic RNA in the 5'-UTR. At low concentration, Gag-Pol and Gag would promote translation, whereas at high concentration, the polyproteins encapsidate genomic RNA and then shut off translation. |
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