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Anti-pan-MAGUK Recombinant Antibody (K28/86) (HX973033)

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  • 100ug
  • 1mg
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概述
货号HX973033
品牌abinScience
种属反应性Drosophila melanogaster (Fruit fly)
应用IHC, IP, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG1, kappa
克隆号K28/86
靶标PSD-95, PSD95, Disks large homolog 4, Synapse-associated protein 90, DLG4, Postsynaptic density protein 95, SAP-90, SAP90
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P78352
RRIDAnti-pan-MAGUK Antibody (K28/86) (abinScience Cat# HX973033, RRID:AB_3727042)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Disks large homolog 4 (Membrane-associated guanylate kinases (MAGUK)) is a ~80 kDa protein. Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly.

1. Brigidi, GS. et al. (2015) Nature communications 6, 8200. PMID: 26334723
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-pan-MAGUK Antibody (K28/86)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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