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InVivoMAb Anti-Human PAUF/ZG16B Antibody (Iv0188) (HB774010)

价格: --
规格:
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HB774010
品牌abinScience
描述
InVivoMAb Anti-Human PAUF Antibody (Iv0188) [Iv0188] (HB774010) is a human monoclonal antibody detecting Pancreatic adenocarcinoma upregulated factor in Blocking, ELISA. Suitable for Human.
种属反应性Human
应用Blocking, ELISA
宿主Human
克隆类型Monoclonal
同种型IgG1, kappa
克隆号Iv0188
靶标Pancreatic adenocarcinoma upregulated factor, PAUF
内毒素水平< 1 EU/mg as determined by LAL method.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q96DA0
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Pancreatic adenocarcinoma up-regulated factor (PAUF) is a ~18 kDa protein. Functions as a lectin that binds to selective commensal dental plaque bacteria, such as Streptococcus vestibularis. Contributes to maintain homeostasis in the oral microbiome by capturing commensal microbes and regulating their growth using a mucin-assisted clearance mechanism. Plays an important role in pancreatic tumor progression and metastasis. Promotes pancreatic cancer cells migration and invasion through the TLR4/MyD88/NF-kappaB signaling pathway, without the involvement of the TLR4/TRIF pathway.

1. Ghosh, S. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2216304120. PMID: 37216558
2. Kim, SA. et al. (2009) Cancer science 100, 828-36. PMID: 19302292
3. Youn, SE. et al. (2022) International journal of molecular sciences 23. PMID: 36232715
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Human PAUF Antibody (Iv0188)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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