Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

VK661013

abinScience

种属反应性

Zaire ebolavirus (ZEBOV) (Zaire Ebola virus)

ELISA, WB

VP35, Polymerase cofactor VP35, Ebola VP35, eVP35

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q05127

Anti-ZEBOV VP35/Polymerase cofactor VP35 Antibody (F9) (abinScience Cat# VK661013, RRID:AB_3727248)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Polymerase cofactor VP35 is a ~37 kDa protein. Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling. Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes. Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes. Part of the external layer of the nucleocapsid, likely tethering the nucleocapsid to the matrix and membrane. Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1.

1. Basler, CF. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 12289-94. PMID: 11027311

2. van Tol, S. et al. (2022) PLoS pathogens 18, e1010532. PMID: 35533195

3. Enterlein, S. et al. (2006) Antimicrobial agents and chemotherapy 50, 984-93. PMID: 16495261

4. Brown, CS. et al. (2014) Journal of molecular biology 426, 2045-58. PMID: 24495995

5. Mühlberger, E. et al. (1999) Journal of virology 73, 2333-42. PMID: 9971816

6. Watanabe, R. et al. (2024) Cell 187, 5587-5603.e19. PMID: 39293445

7. Luthra, P. et al. (2015) Journal of virology 89, 5148-53. PMID: 25741013

8. Leung, DW. et al. (2015) Cell reports 11, 376-89. PMID: 25865894

9. Yen, BC. et al. (2016) Journal of virology 90, 5108-5118. PMID: 26962215

10. Luthra, P. et al. (2013) Cell host & microbe 14, 74-84. PMID: 23870315

For research use only.

SDS-PAGE

SDS-PAGE for Anti-ZEBOV VP35/Polymerase cofactor VP35 Antibody (F9)

产品说明书

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ZEBOV VP35/Polymerase cofactor VP35 Recombinant Antibody (F9) (VK661013)

概述

图片

参考文献

产品说明书

相关产品推荐

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