Anti-Human BIN1 Recombinant Antibody (SAA1499) (HT430013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HT430013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1499

AMPHL, Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, BIN1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O00499

Anti-Human BIN1 Antibody (SAA1499) (abinScience Cat# HT430013, RRID:AB_3727260)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Myc box-dependent-interacting protein 1 (BIN1/Amphiphysin-II) is a ~64 kDa protein. Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis. Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production. In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates.

1. Wu, T. et al. (2014) PloS one 9, e93060. PMID: 24755653

2. Miyagawa, T. et al. (2016) Human molecular genetics 25, 2948-2958. PMID: 27179792

3. Sakamuro, D. et al. (1996) Nature genetics 14, 69-77. PMID: 8782822

4. Dräger, NM. et al. (2017) EMBO reports 18, 2051-2066. PMID: 28893863

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human BIN1 Antibody (SAA1499)

产品说明书

Anti-Human BIN1 Recombinant Antibody (SAA1499).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BIN1 Recombinant Antibody (SAA1499) (HT430013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BIN1 Recombinant Antibody (SAA1499) (HT430013)

概述

图片

参考文献

产品说明书

相关产品推荐

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