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Anti-Human KRAS/K-Ras 2 Recombinant Antibody (SAA1513) (HF904013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HF904013
品牌abinScience
种属反应性Human
应用ELISA
同种型IgG2a, kappa
克隆号SAA1513
靶标c-Ki-ras, RASK2, GTPase KRas, K-Ras 2, c-K-ras, KRAS, Ki-Ras, KRAS2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P01116
RRIDAnti-Human KRAS/K-Ras 2 Antibody (SAA1513) (abinScience Cat# HF904013, RRID:AB_3727274)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

GTPase KRas (K-Ras 2) is a ~21 kDa protein. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Activates MAPK1/MAPK3 resulting in phosphorylation and ultimately degradation of GJA1. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.

1. Gremer, L. et al. (2011) Human mutation 32, 33-43. PMID: 20949621
2. Bernal Astrain, G. et al. (2025) Nature communications 16, 647. PMID: 39809765
3. Yang, MH. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10843-8. PMID: 22711838
4. Zimmermann, G. et al. (2013) Nature 497, 638-42. PMID: 23698361
5. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human KRAS/K-Ras 2 Antibody (SAA1513)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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