







| 货号 | HY262013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA, WB | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1520 | ||||
| 靶标 | IL3, Hematopoietic growth factor, Multipotential colony-stimulating factor, IL-3, Mast cell growth factor, Interleukin-3, P-cell-stimulating factor, MCGF | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P08700 | ||||
| RRID | Anti-Human IL3 Antibody (SAA1520) (abinScience Cat# HY262013, RRID:AB_3727281) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Interleukin-3 (IL3) is a ~17 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB. 1. Guba, SC. et al. (1989) The Journal of clinical investigation 84, 1701-6. PMID: 2556442 2. Okayama, Y. et al. (1993) Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 23, 901-10. PMID: 10779277 3. Hong, L. et al. (2020) Cytokine 136, 155268. PMID: 32889153 4. Luo, XJ. et al. (2012) PloS one 7, e50375. PMID: 23226269 5. Khapli, SM. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 142-51. PMID: 12816992 6. Broughton, SE. et al. (2018) Nature communications 9, 386. PMID: 29374162 7. López, C. et al. (2017) Journal of cellular biochemistry 118, 1330-1340. PMID: 27862234 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human IL3 Antibody (SAA1520)

Detects recombinant human IL3 (Catalog No: HY262012) in indirect ELISA.

Detects recombinant human IL3 (Catalog No: HY262011) in indirect ELISA.

Western blot analysis was performed using anti-IL3 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human IL3 (Catalog No: HY262011)









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