Anti-Human FZD7 Recombinant Antibody (SAA1525) (HF587013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HF587013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1525

Frizzled-7, hFz7, FzE3, Fz-7, FZD7

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O75084

Anti-Human FZD7 Antibody (SAA1525) (abinScience Cat# HF587013, RRID:AB_3727286)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Frizzled-7 (FZD7) is a ~63 kDa protein. Receptor for Wnt proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Activation by WNT8 induces expression of beta-catenin target genes.

1. Aznar, N. et al. (2015) eLife 4, e07091. PMID: 26126266

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human FZD7 Antibody (SAA1525)

产品说明书

Anti-Human FZD7 Recombinant Antibody (SAA1525).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FZD7 Recombinant Antibody (SAA1525) (HF587013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FZD7 Recombinant Antibody (SAA1525) (HF587013)

概述

图片

参考文献

产品说明书

相关产品推荐

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