Anti-Human LCK Recombinant Antibody (SAA1559) (HY018013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HY018013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1559

T cell-specific protein-tyrosine kinase, LSK, LCK, Protein YT16, p56-LCK, Tyrosine-protein kinase Lck, Lymphocyte cell-specific protein-tyrosine kinase, Proto-oncogene Lck, Leukocyte C-terminal Src kinase

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P06239

Anti-Human LCK Antibody (SAA1559) (abinScience Cat# HY018013, RRID:AB_3727320)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Tyrosine-protein kinase Lck is a ~58 kDa protein. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR-CD3 complex. LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR-CD3 signaling pathway.

1. Barber, EK. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 3277-81. PMID: 2470098

2. Du, J. et al. (2025) Cell 188, 4025-4042.e20. PMID: 40592325

3. Jung, SH. et al. (2016) Journal of immunology (Baltimore, Md. : 1950) 197, 942-52. PMID: 27335501

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human LCK Antibody (SAA1559)

产品说明书

Anti-Human LCK Recombinant Antibody (SAA1559).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LCK Recombinant Antibody (SAA1559) (HY018013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LCK Recombinant Antibody (SAA1559) (HY018013)

概述

图片

参考文献

产品说明书

相关产品推荐

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