

| 货号 | HX905013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1576 | ||||
| 靶标 | MCT 1, SLC16A1, Monocarboxylate transporter 1, MCT1, Solute carrier family 16 member 1 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P53985 | ||||
| RRID | Anti-Human SLC16A1/MCT1 Antibody (SAA1576) (abinScience Cat# HX905013, RRID:AB_3727337) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Monocarboxylate transporter 1 (SLC16A1/MCT1) is a ~53 kDa protein. Bidirectional proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, acetate and the ketone bodies acetoacetate and beta-hydroxybutyrate, and thus contributes to the maintenance of intracellular pH. The transport direction is determined by the proton motive force and the concentration gradient of the substrate monocarboxylate. MCT1 is a major lactate exporter. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis. 1. Galić, S. et al. (2003) The Biochemical journal 376, 413-22. PMID: 12946269 2. Reddy, A. et al. (2020) Cell 183, 62-75.e17. PMID: 32946811 3. Wang, N. et al. (2021) Cell 184, 370-383.e13. PMID: 33333023 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human SLC16A1/MCT1 Antibody (SAA1576)



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