

| 货号 | HB750013 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 种属反应性 | Human | ||||
| 应用 | ELISA | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | SAA1593 | ||||
| 靶标 | CD53, Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25, TSPAN25, MOX44 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P19397 | ||||
| RRID | Anti-Human CD53 Antibody (SAA1593) (abinScience Cat# HB750013, RRID:AB_3727354) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Leukocyte surface antigen CD53 is a ~24 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Plays a role in the activation of monocytes and B-cells. Acts as an essential regulator of B-cell development by promoting interleukin-7 receptor/IL7R signaling. Also promotes, in B-cells, the BCR signaling by recruiting PKC to the plasma membrane in order to phosphorylate its substrates. 1. Zuidscherwoude, M. et al. (2017) Science signaling 10. PMID: 28487417 2. Yang, Y. et al. (2020) The EMBO journal 39, e105246. PMID: 32974937 3. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951 4. Olweus, J. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 707-16. PMID: 8335905 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human CD53 Antibody (SAA1593)



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