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Anti-Human CD300f/CD300LF Recombinant Antibody (SAA1608) (HV211013)

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规格:
  • 50ug
  • 100ug
  • 1mg
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  • 参考文献

  • 产品说明书

概述
货号HV211013
品牌abinScience
种属反应性Human
应用ELISA
同种型IgG2a, kappa
克隆号SAA1608
靶标IREM1, Immunoglobulin superfamily member 13, NK inhibitory receptor, CD300 antigen-like family member F, CD300F, CD300LF, CLM-1, IGSF13, NKIR, IREM-1, Immune receptor expressed on myeloid cells 1, CMRF35-like molecule 1, CD300f, IgSF13, CLM1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q8TDQ1
RRIDAnti-Human CD300f/CD300LF Antibody (SAA1608) (abinScience Cat# HV211013, RRID:AB_3727369)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

CMRF35-like molecule 1 (CD300f/CD300LF) is a ~32 kDa protein. Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4).

1. Alvarez-Errico, D. et al. (2004) European journal of immunology 34, 3690-701. PMID: 15549731
2. Izawa, K. et al. (2014) The Journal of allergy and clinical immunology 133, 270-3.e1-7. PMID: 24035150
3. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CD300f/CD300LF Antibody (SAA1608)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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