Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616) (HV606013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HV606013

abinScience

种属反应性

Human

ELISA

IgG2a, kappa

SAA1616

PRSC1, Legumain, Asparaginyl endopeptidase, LGMN, Protease, cysteine 1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q99538

Anti-Human LGMN/Legumain Antibody (SAA1616) (abinScience Cat# HV606013, RRID:AB_3727377)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Legumain (LGMN) is a ~49 kDa protein. Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules.

1. Dall, E. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 10940-5. PMID: 23776206

2. Manoury, B. et al. (1998) Nature 396, 695-9. PMID: 9872320

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human LGMN/Legumain Antibody (SAA1616)

产品说明书

Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616) (HV606013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LGMN/Legumain Recombinant Antibody (SAA1616) (HV606013)

概述

图片

参考文献

产品说明书

相关产品推荐

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