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Anti-Human ABCC1 Recombinant Antibody (SAA1629) (HW501013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

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概述
货号HW501013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1629
靶标Leukotriene C(4) transporter, ABCC1, MRP, Multidrug resistance-associated protein 1, MRP1, Glutathione-S-conjugate-translocating ATPase ABCC1, LTC4 transporter, ATP-binding cassette sub-family C member 1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P33527
RRIDAnti-Human ABCC1 Antibody (SAA1629) (abinScience Cat# HW501013, RRID:AB_3727390)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Multidrug resistance-associated protein 1 (ABCC1) is a ~171 kDa protein. Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation.

1. Sjölinder, M. et al. (1999) Journal of lipid research 40, 439-46. PMID: 10064732
2. Robbiani, DF. et al. (2000) Cell 103, 757-68. PMID: 11114332
3. Conseil, G. et al. (2006) The Journal of biological chemistry 281, 43-50. PMID: 16230346
4. Leier, I. et al. (1994) The Journal of biological chemistry 269, 27807-10. PMID: 7961706
5. Stride, BD. et al. (1997) Molecular pharmacology 52, 344-53. PMID: 9281595
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human ABCC1 Antibody (SAA1629)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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