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Anti-Human RAB10 Recombinant Antibody (SAA1654) (HX991013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HX991013
品牌abinScience
种属反应性Human
应用ELISA
同种型IgG2a, kappa
克隆号SAA1654
靶标Ras-related protein Rab-10, RAB10
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P61026
RRIDAnti-Human RAB10 Antibody (SAA1654) (abinScience Cat# HX991013, RRID:AB_3727415)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Ras-related protein Rab-10 (RAB10) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB10 is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, RAB10 regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response.

1. Hutagalung, AH. et al. (2011) Physiological reviews 91, 119-49. PMID: 21248164
2. Babbey, CM. et al. (2006) Molecular biology of the cell 17, 3156-75. PMID: 16641372
3. English, AR. et al. (2013) Nature cell biology 15, 169-78. PMID: 23263280
4. Dhekne, HS. et al. (2018) eLife 7. PMID: 30398148
5. Lucken-Ardjomande Häsler, S. et al. (2020) The Journal of cell biology 219. PMID: 32344433
6. Eguchi, T. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E9115-E9124. PMID: 30209220
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human RAB10 Antibody (SAA1654)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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