Anti-Human DSC2 Recombinant Antibody (SAA1658) (HX236013)

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规格：

50ug
100ug
1mg

数量：

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概述
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参考文献
产品说明书

HX236013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

IgG2a, kappa

SAA1658

Desmosomal glycoprotein II, Desmocollin-2, DSC2, DSC3, Cadherin family member 2, CDHF2, Desmosomal glycoprotein III, Desmocollin-3

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q02487

Anti-Human DSC2 Antibody (SAA1658) (abinScience Cat# HX236013, RRID:AB_3727419)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Desmocollin-2 (DSC2) is a ~99 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Promotes timely incorporation of DSG2 into desmosome intercellular junctions and promotes interaction of desmosome cell junctions with intermediate filament cytokeratin, via modulation of DSP phosphorylation. Plays an important role in desmosome-mediated maintenance of intestinal epithelial cell intercellular adhesion strength and barrier function. Positively regulates wound healing of intestinal mucosa via promotion of epithelial cell migration, and also plays a role in mechanotransduction of force between intestinal epithelial cells and extracellular matrix. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

1. Raya-Sandino, A. et al. (2021) Molecular biology of the cell 32, 753-768. PMID: 33596089

2. Flemming, S. et al. (2020) Molecular biology of the cell 31, 407-418. PMID: 31967937

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human DSC2 Antibody (SAA1658)

产品说明书

Anti-Human DSC2 Recombinant Antibody (SAA1658).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DSC2 Recombinant Antibody (SAA1658) (HX236013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human DSC2 Recombinant Antibody (SAA1658) (HX236013)

概述

图片

参考文献

产品说明书

相关产品推荐

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