Anti-Human RSPO1 Recombinant Antibody (SAA1690) (HS709013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HS709013

abinScience

种属反应性

Human, Mouse

ELISA

IgG2a, kappa

SAA1690

R-spondin-1, hRspo1, RSPO1, Roof plate-specific spondin-1

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q2MKA7

Anti-Human RSPO1 Antibody (SAA1690) (abinScience Cat# HS709013, RRID:AB_3727451)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

R-spondin-1 (RSPO1) is a ~28 kDa protein. Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

1. Szenker-Ravi, E. et al. (2018) Nature 557, 564-569. PMID: 29769720

2. Binnerts, ME. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 14700-5. PMID: 17804805

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

SDS-PAGE

SDS-PAGE for Anti-Human RSPO1 Antibody (SAA1690)

产品说明书

Anti-Human RSPO1 Recombinant Antibody (SAA1690).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RSPO1 Recombinant Antibody (SAA1690) (HS709013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human RSPO1 Recombinant Antibody (SAA1690) (HS709013)

概述

图片

参考文献

产品说明书

相关产品推荐

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