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Anti-Human BMP1 Recombinant Antibody (SAA1793) (HY077013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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概述
货号HY077013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1793
靶标PCOLC, Mammalian tolloid protein, mTld, Bone morphogenetic protein 1, PCP, BMP-1, Procollagen C-proteinase, BMP1
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P13497
RRIDAnti-Human BMP1 Antibody (SAA1793) (abinScience Cat# HY077013, RRID:AB_3727555)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation.

1. N'Diaye, EN. et al. (2021) American journal of physiology. Cell physiology 320, C162-C174. PMID: 33206546
2. Anastasi, C. et al. (2020) Science signaling 13. PMID: 32636307
3. Wang, J. et al. (2021) Journal of periodontology 92, 1018-1029. PMID: 33169406
4. Rosell-García, T. et al. (2019) The Journal of biological chemistry 294, 11087-11100. PMID: 31152061
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human BMP1 Antibody (SAA1793)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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