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Anti-Human MAP3K14 Recombinant Antibody (SAA1891) (HA232013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HA232013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1891
靶标NF-kappa-beta-inducing kinase, NIK, HsNIK, Mitogen-activated protein kinase kinase kinase 14, MAP3K14, Serine/threonine-protein kinase NIK
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q99558
RRID

Anti-Human MAP3K14 Antibody (SAA1891) (abinScience Cat# HA232013, RRID:AB_3727655)
_x005F_x000D_

状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Mitogen-activated protein kinase kinase kinase 14 (MAP3K14) is a ~104 kDa protein. Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Phosphorylates CHUK/IKKA, thereby promoting proteolytic processing of NFKB2/P100, which leads to NF-kappa-B activation via the non-canonical pathway. Has an essential role in the non-canonical NF-kappa-B signaling that regulates genes encoding molecules involved in B-cell survival, lymphoid organogenesis, and immune response. Could act in a receptor-selective manner.

1. Willmann, KL. et al. (2014) Nature communications 5, 5360. PMID: 25406581
2. Schlechter, N. et al. (2017) Frontiers in immunology 8, 1624. PMID: 29230214
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human MAP3K14 Antibody (SAA1891)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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