首页 > 产品中心 > 抗体 > 一抗

Anti-Human CADM1 Recombinant Antibody (SAA1897) (HA183013)

价格:
规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HA183013
品牌abinScience
种属反应性Human
应用ELISA
宿主Mouse
克隆类型Monoclonal
同种型IgG2a, kappa
克隆号SAA1897
靶标SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9BY67
RRID

Anti-Human CADM1 Antibody (SAA1897) (abinScience Cat# HA183013, RRID:AB_3727661)
_x005F_x005F_x000D_

状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Cell adhesion molecule 1 (CADM1) is a ~48 kDa protein. Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM1 in vivo. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo.

1. Masuda, M. et al. (2002) The Journal of biological chemistry 277, 31014-9. PMID: 12050160
2. Moiseeva, EP. et al. (2012) Cellular and molecular life sciences : CMLS 69, 2751-64. PMID: 22438059
3. Boles, KS. et al. (2005) Blood 106, 779-86. PMID: 15811952
4. Furuno, T. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 174, 6934-42. PMID: 15905536
5. Kuramochi, M. et al. (2001) Nature genetics 27, 427-30. PMID: 11279526
6. Yageta, M. et al. (2002) Cancer research 62, 5129-33. PMID: 12234973
7. Ito, A. et al. (2003) Laboratory investigation; a journal of technical methods and pathology 83, 1175-83. PMID: 12920246
NoteFor research use only.
Isotype ControlMouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human CADM1 Antibody (SAA1897)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐