

| 货号 | HB859023 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 应用 | IHC, WB | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | L76/36 | ||||
| 靶标 | Voltage-gated K(+) channel HuKIV, Voltage-gated potassium channel subunit Kv1.2, NGK1, KCNA2, Potassium voltage-gated channel subfamily A member 2, Voltage-gated potassium channel HBK5 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P16389 | ||||
| RRID | Anti-Kv1.2 K+ channel Antibody (L76/36) (abinScience Cat# HB859023, RRID:AB_3728140) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Potassium voltage-gated channel subfamily A member 2 (KCNA2/Kv1.2 K+ channel) is a ~56 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, KCNA6, KCNA7, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel. 1. Imbrici, P. et al. (2000) Pflugers Archiv : European journal of physiology 441, 257-62. PMID: 11211111 2. Ramaswami, M. et al. (1990) Molecular and cellular neurosciences 1, 214-23. PMID: 19912772 3. Lee, JH. et al. (2013) Neuroscience letters 548, 143-8. PMID: 23769686 4. Po, S. et al. (1993) Circulation research 72, 1326-36. PMID: 8495559 5. Chen, P. et al. (2010) The Journal of biological chemistry 285, 14882-14889. PMID: 20220134 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Kv1.2 K+ channel Antibody (L76/36)



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