

| 货号 | HC627023 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 应用 | IHC, WB | ||||
| 宿主 | Mouse | ||||
| 克隆类型 | Monoclonal | ||||
| 同种型 | IgG2a, kappa | ||||
| 克隆号 | N1/55 | ||||
| 靶标 | CAMKG, CAMK-II, CAMK, CAMK2G, CaM kinase II subunit gamma, CaMK-II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit gamma | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | Q63633 | ||||
| RRID | Anti-KCC2 Antibody (N1/55) (abinScience Cat# HC627023, RRID:AB_3728370) | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Solute carrier family 12 member 5 (SLC12A5/KCC2) is a ~126 kDa protein. Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition. Involved in the regulation of dendritic spine formation and maturation. 1. Casula, S. et al. (2001) The Journal of biological chemistry 276, 41870-8. PMID: 11551954 2. Rivera, C. et al. (1999) Nature 397, 251-5. PMID: 9930699 3. Fiumelli, H. et al. (2013) Cerebral cortex (New York, N.Y. : 1991) 23, 378-88. PMID: 22345354 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-KCC2 Antibody (N1/55)



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