Anti-Optineurin Recombinant Antibody (6A7.1) (HP451013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP451013

abinScience

种属反应性

Human

IHC, WB

IgG2a

6A7.1

NRP, TFIIIA-IntP, Huntingtin-interacting protein 7, HIP-7, Huntingtin yeast partner L, Transcription factor IIIA-interacting protein, NEMO-related protein, E3-14.7K-interacting protein, GLC1E, HIP7, HYPL, FIP-2, Huntingtin-interacting protein L, Optic neuropathy-inducing protein, OPTN, Optineurin, FIP2

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q96CV9

Anti-Optineurin Antibody (6A7.1) (abinScience Cat# HP451013, RRID:AB_3728971)
_x005F_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Optineurin (OPTN) is a ~65 kDa protein. Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. Plays a role in the activation of innate immune response during viral infection. Mechanistically, recruits TBK1 at the Golgi apparatus, promoting its trans-phosphorylation after RLR or TLR3 stimulation. In turn, activated TBK1 phosphorylates its downstream partner IRF3 to produce IFN-beta/IFNB1.

1. Fifita, JA. et al. (2017) Amyotrophic lateral sclerosis & frontotemporal degeneration 18, 126-133. PMID: 27534431

2. Pourcelot, M. et al. (2016) BMC biology 14, 69. PMID: 27538435

3. Vaibhava, V. et al. (2012) Journal of cell science 125, 5026-39. PMID: 22854040

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

SDS-PAGE

SDS-PAGE for Anti-Optineurin Antibody (6A7.1)

产品说明书

Anti-Optineurin Recombinant Antibody (6A7.1).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

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试剂盒

实验相关试剂

Anti-Optineurin Recombinant Antibody (6A7.1) (HP451013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Optineurin Recombinant Antibody (6A7.1) (HP451013)

概述

图片

参考文献

产品说明书

相关产品推荐

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