Anti-Bacillus anthracis cya/EF/Edema factor Recombinant Antibody (B1) (JN040023)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

JN040023

abinScience

种属反应性

Bacillus anthracis

ELISA, SPR

IgG2a

Calmodulin-sensitive adenylate cyclase, 4.6.1.1, ATP pyrophosphate-lyase, Adenylyl cyclase, Anthrax edema toxin adenylate cyclase component, Edema factor, EF, cya, pXO1-122, BXA0141, GBAA_pXO1_0142, Bacillus anthracis

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

P40136

Anti-Bacillus anthracis cya/EF/Edema factor Antibody (B1) (abinScience Cat# JN040023, RRID:AB_3729008)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Calmodulin-sensitive adenylate cyclase (cya/EF) is a ~92 kDa protein. Edema factor (EF), which constitutes one of the three proteins composing the anthrax toxin, causes edema in the host. Acts as a calmodulin-dependent adenylyl cyclase by converting ATP to cAMP, leading to dramatic elevation of intracellular cAMP levels in the host, thereby causing edema. EF is not toxic by itself and only acts as an edema factor when associated with protective antigen (PA) to form the edema toxin (EdTx). Required for the survival of germinated spores within macrophages at the early stages of infection.

1. Drum, CL. et al. (2002) Nature 415, 396-402. PMID: 11807546

2. Xia, ZG. et al. (1990) The Journal of biological chemistry 265, 6517-20. PMID: 2108958

3. Leppla, SH. (1982) Proceedings of the National Academy of Sciences of the United States of America 79, 3162-6. PMID: 6285339

4. Kumar, P. et al. (2001) Infection and immunity 69, 6532-6. PMID: 11553601

5. Guidi-Rontani, C. et al. (2001) Molecular microbiology 42, 931-8. PMID: 11737637

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Bacillus anthracis cya/EF/Edema factor Antibody (B1)

产品说明书

Anti-Bacillus anthracis cya/EF/Edema factor Recombinant Antibody (B1).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Bacillus anthracis cya/EF/Edema factor Recombinant Antibody (B1) (JN040023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Bacillus anthracis cya/EF/Edema factor Recombinant Antibody (B1) (JN040023)

概述

图片

参考文献

产品说明书

相关产品推荐

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