Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12) (JN824013)

价格:

规格：

50ug
100ug
1mg

数量：

一键复制产品信息

概述
图片
参考文献
产品说明书

JN824013

abinScience

种属反应性

Neisseria meningitidis

ELISA

IgG2a

Factor H binding protein, fHbp, Genome-derived Neisseria antigen 1870, GNA1870, Lipoprotein 2086, LP2086, fhbP, NMB1870

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q9JXV4

Anti-Neisseria meningitidis FHBP Antibody (1A12) (abinScience Cat# JN824013, RRID:AB_3729061)
_x005F_x000D_

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Factor H binding protein (FHBP) is a ~28 kDa protein. A bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH), binding contributes to the avoidance of complement-mediated lysis by N.meningitidis. Binding of fH to the bacteria surface is independent of bacterial sialic acid moieties. fH binding affinity is high enough that it may sequester plasma fH, depleting its circulating levels and de-regulating complement in the host (Probable). This protein induces high levels of bactericidal antibodies in mice.

1. Schneider, MC. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 7566-75. PMID: 16751403

2. Masignani, V. et al. (2003) The Journal of experimental medicine 197, 789-99. PMID: 12642606

3. Fletcher, LD. et al. (2004) Infection and immunity 72, 2088-100. PMID: 15039331

4. Giuliani, MM. et al. (2005) Infection and immunity 73, 1151-60. PMID: 15664958

5. Scarselli, M. et al. (2011) Science translational medicine 3, 91ra62. PMID: 21753121

6. Johnson, S. et al. (2012) PLoS pathogens 8, e1002981. PMID: 23133374

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Neisseria meningitidis FHBP Antibody (1A12)

产品说明书

Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12) (JN824013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Neisseria meningitidis FHBP Recombinant Antibody (1A12) (JN824013)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价