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Anti-Neisseria meningitidis fhbP/GNA1870/LP2086 Recombinant Antibody (SAA2081) (JN824033)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

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概述
货号JN824033
品牌abinScience
种属反应性Neisseria meningitidis
应用ELISA
同种型IgG1, kappa
克隆号SAA2081
靶标fhbP
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号Q9JXV4, E6MV22, Q9JXV4
RRIDAnti-Neisseria meningitidis fhbP/GNA1870/LP2086 Antibody (SAA2081) (abinScience Cat# JN824033, RRID:AB_3729314)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Factor H binding protein (FHBP) is a ~28 kDa protein. A bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH), binding contributes to the avoidance of complement-mediated lysis by N.meningitidis. Binding of fH to the bacteria surface is independent of bacterial sialic acid moieties. fH binding affinity is high enough that it may sequester plasma fH, depleting its circulating levels and de-regulating complement in the host (Probable). This protein induces high levels of bactericidal antibodies in mice.

1. Schneider, MC. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 7566-75. PMID: 16751403
2. Masignani, V. et al. (2003) The Journal of experimental medicine 197, 789-99. PMID: 12642606
3. Fletcher, LD. et al. (2004) Infection and immunity 72, 2088-100. PMID: 15039331
4. Giuliani, MM. et al. (2005) Infection and immunity 73, 1151-60. PMID: 15664958
5. Scarselli, M. et al. (2011) Science translational medicine 3, 91ra62. PMID: 21753121
6. Johnson, S. et al. (2012) PLoS pathogens 8, e1002981. PMID: 23133374
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Neisseria meningitidis fhbP/GNA1870/LP2086 Antibody (SAA2081).

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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